Intronic SNPs and Genetic Diseases: A Review
نویسندگان
چکیده
Introns qualify as Noncoding nucleotide sequences. In splicing, some segments of the RNA transcript (introns) are eliminated, other (exons) joining together in formation coding RNAs (mRNA, rRNA and tRNA). Also, Non-coding genes parts intronic. On average, there 7.8 introns 8.8 exons per human gene. Single polymorphisms (SNPs) existed various positions through gene, promoters, alternating regions introns, terminator, addition to UTRs, untranslated (5'- 3'-).Therefore, many diseases have been associated with SNPs different mechanisms. current review, we will discuss several genetic epigenetic regulations included identifying disease susceptibility linked numerous existing intronic region.
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ژورنال
عنوان ژورنال: International journal for research in applied sciences and biotechnology
سال: 2021
ISSN: ['2349-8889']
DOI: https://doi.org/10.31033/ijrasb.8.2.36